Vol. 70 No. 3 (2026)

Original research

Suspended solids particles exposure to the blood of patients with bronchial asthma of varying severity in vitro

Elena Viktorovna Kondratyeva, Sergei Ivanovich Kolesnikov, Tatyana Isaakovna Vitkina

5-16
Study of expression alterations in genes associated with epithelial-mesenchymal transition in lung cancer

Anna Alexandrovna Smirnova, Yana Alekseevna Yakubenko, Vitaly Igorevich Loginov, Alexey Mikhailovich Burdennyy, Olga Borisovna Chekhonina, Irina Yuryevna Lyalina, Tatyana Pavlovna Kazubskaya, Irina Valeryevna Pronina

17-28
Inhibition of the PI3K/AKT signaling pathway in tumor cells and reduction of their proliferative activity by 5-oxo-7-phenylamino-4,5-dihydropyrazolo[1,5-a]pyrimidine-3- carbonitrile

Vsevolod Viktorovich Melekhin, Maria Dmitrievna Tokhtueva, Anastasia Vladislavovna Paramonova, Elena Igorevna Andreeva, Anatoly Ivanovich Matern, Daniil Nikolaevich Lyapustin, Irina Vladimirovna Marusich, Dilya Failevna Faizullina, Svetlana Konstantinovna Kotovskaya, Vladimir Leonidovich Rusinov, Oleg Germanovich Makeev

29-43
Analysis of homo- / heteroplasmy levels of mtDNA and MT-CYB gene expression in monocytes from obese patients

Maria Alexandrovna Vulf, Maria Andreevna Bograya, Sophia Sergeevna Voronova, Maria Andreevna Beletskaya, Vladimir Vladimirovich Malashchenko, Larisa Sergeevna Litvinova

44-57
Fibroblast activating protein-α (FAP-α) and perlecan as potential biomarkers of idiopathic epiretinal membrane (preliminary results)

Shirin Alievna Aliyeva, Svetlana Valeryevna Kolesnik, Dmitry Sergeevich Ostrovsky, Anton Igorevich Kolesnik, Dmitry Gennadyevich Arsyutov, Sergey Anatolyevich Borzenok

58-65
Polyclonal antibodies to glutamate affect calcium homeostasis in primary neuroglial culture cells

Alexey Alekseevich Zherdev, Luchia Alexandrovna Vetrile, Irina Alexandrovna Zakharova, Zanda Valerievna Bakaeva, Tatyana Viktorovna Davydova, Alexander Mikhailovich Surin

66-76
Alteration of pain sensitivity by intermittent stress in female Wistar rats

Lada Vladimirovna Kuznetsova, Natalya Yuryevna Klishina, Margarita Nikolaevna Karpova, Mikhail Lvovich Kukushkin

77-84
Delayed effects of the BDNF mimetic GSB-106 on behavior in Wistar rats with experimental autism spectrum disorder

Elena Vladimirovna Savinkova, Inga Gennadievna Kapitsa, Alexandrovna

85-93
Blood platelet count and aggregation as outcome markers in patients with abdominal sepsis

Mikhail Vladimirovich Osikov, Alexey Gennadievich Konashov, Andrey Vladimirovich Gusev, Margarita Sergeevna Boyko, Darya Eduardovna Myakotina

94-103
The relationship between the hemodynamic effects of nitroprusside and its lifetime in rat blood plasma

Владимир Юрьевич Титов, Sergey Nikolaevich Kalabushev, Konstantin Nikolaevich Lapin, Polina Alexandrovna Fonova, Vasilisa Alekseevna Petrunina, Sofia Alekseevna Kuptsova, Ivan Alexandrovich Ryzhkov, Anatoly Nikolaevich Osipov

104-114
Changes in specific markers of endothelial dysfunction in blood in experimental metabolic syndrome

Mariam Borisovna Zaurova, Tatiana Pavlovna Makalish , Ekaterina Viktorovna Kovrizhnyh , Irina Ivanovna Fomochkina, Anatoly Vladimirovich Kubyshkin

115-122
Microfluidic chips to overcome male factor infertility: selection of sperm with intact DNA for ART programs

Ivan Dmitrievich Gromenko, Shamil Narimanovich Galimov, Peter Frantsevich Litvitsky, Polina Alexandrovna Podobina, Elmira Fanisovna Galimova, Kamil Shamilevich Galimov

123-128
A look at the pathogenesis of preeclampsia in gestational diabetes mellitus through the lens of proteomics

Andrey Sergeevich Anikeev, Sergey Georgievich Morozov, Nadezhda Mikhailovna Startseva, rtur Tigranovich Kopylov, Elena Nikolaevna Kozhevnikova, Alexander Alexandrovich Sidyakin, Olga Konstantinovna Doronina, Elizaveta Sergeevna Anikeeva, Shavkat S.A. Imrayzik

129-140
Protein Oxidative Modification as a Biomarker in the Correction of Depression-Like States: A Comparative Analysis of the Efficacy of Natural Antioxidants (Experimental Study)

Polina Mikhailovna Moskvitina, Olga Nikolaevna Pavlova, Olga Nikolaevna Gulenko, Aleksandr Ivanovich Budaev, Igor Viktorovich Shirolapov

141-152
Anti-anxiety, antidepressant and analgesic effects of mesodiencephalic modulation in intact and stressed BALB/c mice

Evgeny Maksimovich Frolov, Raul Dzhabrailovich Kazimov, Alexander Yurievich Nuzhdin, Maxim Yurievich Frolov, Alexander Viktorovich Melerzanov

153-163

Methods

Repair of cranial bones after contouring using polymethacrylate-based alloimplant

Yazid Hani Mnaweef Altahkhan, Andrey Alekseevich Orlov, Igor Borisovich Ganshin

164-174

Reviews

The role of hematological indices in liver fibrosis assessment

Arina Yurievna Maksimova, Anna Anatolievna Tomilova , Vladimir Victorovich Bazarnyi

175-183
Cytochrome P450 and assisted reproductive technologies: from the molecular basics of metabolism to the personalization of superovulation stimulation protocols

Anna Vasilyevna Lapshtaeva, Ivan Vitalievich Sychev, Darya Vladimirovna Puzakova, Julia Alexandrovna Kostina, Dmitry Alekseevich Sychev

184-198
The role of genetic polymorphisms of transporters and enzymes in insufficient effectiveness of hmg-coa reductase inhibitor treatment: a literature review

Nadezhda Vladimirovna Izmozherova, Victoria Alekseevna Kostash, Muraz Akbar oglu Shambatov, Elena Vladimirovna Kudryavtseva, Polina Vladimirovna Tsipres, Artem Anatolyevich Popov

199-212
Pathophysiological mechanisms of action of targeted therapy in the treatment of polypous rhinosinusitis

Anna Mikhailovna Lazareva, Olga Valentinovna Smirnova

213-221

Original research

Suspended solids particles exposure to the blood of patients with bronchial asthma of varying severity in vitro

Study of expression alterations in genes associated with epithelial-mesenchymal transition in lung cancer

Inhibition of the PI3K/AKT signaling pathway in tumor cells and reduction of their proliferative activity by 5-oxo-7-phenylamino-4,5-dihydropyrazolo[1,5-a]pyrimidine-3- carbonitrile

Analysis of homo- / heteroplasmy levels of mtDNA and MT-CYB gene expression in monocytes from obese patients

Fibroblast activating protein-α (FAP-α) and perlecan as potential biomarkers of idiopathic epiretinal membrane (preliminary results)

Polyclonal antibodies to glutamate affect calcium homeostasis in primary neuroglial culture cells

Alteration of pain sensitivity by intermittent stress in female Wistar rats

Delayed effects of the BDNF mimetic GSB-106 on behavior in Wistar rats with experimental autism spectrum disorder

Blood platelet count and aggregation as outcome markers in patients with abdominal sepsis

The relationship between the hemodynamic effects of nitroprusside and its lifetime in rat blood plasma

Changes in specific markers of endothelial dysfunction in blood in experimental metabolic syndrome

Microfluidic chips to overcome male factor infertility: selection of sperm with intact DNA for ART programs

A look at the pathogenesis of preeclampsia in gestational diabetes mellitus through the lens of proteomics

Protein Oxidative Modification as a Biomarker in the Correction of Depression-Like States: A Comparative Analysis of the Efficacy of Natural Antioxidants (Experimental Study)

Anti-anxiety, antidepressant and analgesic effects of mesodiencephalic modulation in intact and stressed BALB/c mice

Methods

Repair of cranial bones after contouring using polymethacrylate-based alloimplant

Reviews

The role of hematological indices in liver fibrosis assessment

Cytochrome P450 and assisted reproductive technologies: from the molecular basics of metabolism to the personalization of superovulation stimulation protocols

The role of genetic polymorphisms of transporters and enzymes in insufficient effectiveness of hmg-coa reductase inhibitor treatment: a literature review

Pathophysiological mechanisms of action of targeted therapy in the treatment of polypous rhinosinusitis

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