Impact of postconditioning of the heart on necrosis, apoptosis, oncosis, autophagy of cardiomyocytes

Abstract

Postconditioning limits cardiomyocyte necrosis induced by reperfusion. Antinecrotic effect postconditioning is limited by strict time limits and depends on the duration of ischemia postconditioning protocol used. The most of the publications shows that postconditioning inhibits apoptosis of cardiomyocytes evoked by reperfusion. There is evidence that postconditioning prevents reoxygenation oncosis of cardiac cells and enhances autophagy of cardiomyocytes.