To the 50^-th anniversary of the journal
«Pathological physiology and experimental therapy»

In 1957 there occurred a significant event in russian medical science: for the first time a special scientific journal was created, intended to become the printed organ of pathophysiologists. The creation of this journal was predetermined by the entire course of the historical development of the national higher medical school and experimental medicine.

Throughout the world, the term “pathophysiology” is used on a par with the term “experimental pathology”, introduced by François Magendie (1783–1855), Claude Bernard (1813–1873) and V.V. Pashutin (1845–1901) — the founders of the experimental method in medicine.

In the history of Russian medical science, the initial period of the development of the discipline “pathological physiology” ends in 1874 with the opening by V.V. Pashutin the first in Russia department of general and experimental pathology in Kazan University. Prior to this, questions of general pathology and pathological physiology were presented in courses and departments of pathological anatomy, physiology, and therapy. Although the department named “Department of Pathological Anatomy and Pathological Physiology” was organized in Moscow University already in 1849 on the initiative of AA. Polunin, but its own character as predominantly not speculative, but experimental discipline, based on the creation of a model of a disease, pathophysiology only gradually acquired through the works of numerous scientists.

(Excerpt from the jubilee article for the 50th anniversary of the journal full text of which can be found in issue 1 for 2007)