Patologicheskaya Fiziologiya i Eksperimental'naya Terapiya (Pathological physiology and experimental therapy)

Boris Borisovich Moroz, Editor-in-Chief of the Journal «Pathological Physiology and Experimental Therapy», is a well-known pathophysiologist and radiobiologist,Doctor of Medical Sciences, Professor, Academician of the Russian Academy of Sciences.

B.B. Moroz graduated with honors from the medical faculty of the 1st Moscow Sechenov Medical Institute, and completed his postgraduate studies at the Institute of Biophysics of the USSR Ministry of Health. In 1952 he defended his candidate thesis and in 1967 his doctoral thesis. Boris Borisovich worked as Head of Department, was Deputy Director of "Biophysics Institute". Currently he is working at A.I. Burnazyan Federal Medical Biophysical Center, Head of Radiation Pathology Laboratory.

In 1978 he was elected Corresponding Member, in 1988 – Academician of AMS USSR.

The principal scientific works of B.B. Moroz were devoted to pathogenesis of radiation injuries caused by external and internal radiation, he described changes in organs and systems, and disclosed some mechanisms of their development under the action on the organism of incorporated highly toxic radionuclide polonium-210.

Investigation of the mechanisms underlying the development of gastrointestinal syndrome in acute radiation disease established patterns of absorption and digestion disorders, developed a scheme of complete parenteral nutrition for clinical conditions. Mechanisms of postradiational hypercorticism development and the role of glucocorticoids in the course of radiation disease were established under the supervision of B.B. Moroz. The importance of emotional stress in relation to radiation safety was studied. The fact of summation of damaging effects and decrease of radioprotectors efficiency under combined exposure of the organism to ionizing radiation and emotional overstrain was proved. It was shown that the use of anxiolytics eliminated the negative effects of severe emotional stress. The notion of a regulatory role of endogenous glucocorticoids in the processes of hematopoietic stem cell recirculation was experimentally substantiated, it was shown that glucocorticoids in low doses influence the migration and recirculation of hematopoietic stem cells through the system of T-lymphocytes. It was found that mesenchymal stem cells enhance regenerative processes in local radiation injury.

B.B. Moroz was for many years a deputy of All-Union and then Russian scientific society of pathophysiologists (1970−2000), a scientific secretary and a deputy executive editor of the department “Pathological Physiology” of the Great Medical Encyclopedia (1969−1990), a deputy editor-in-chief of the special journal (1964−1990). Since 1984 he is the Editor-in-Chief of the journal “Pathological Physiology and Experimental Therapy”, the major printed organ of pathophysiology.

Boris Borisovich Moroz was awarded with the Order of Labor Red Banner (1966), the Order of Honor (1998), medals, badges of honor “Veteran of Nuclear Power and Industry” (2006), the Golden Cross of Russian Federal Medical and Biological Agency (2012) and other awards.