Taste perception during clinical symptom complex of gastroesophageal reflux disease

  • S. M. Budylina A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia
  • L. A. Dmitrieva A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia
  • N. V. Kostina A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia
  • O. A. Georgieva A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia
  • S. S. Pertsov A.I. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia; P.K. Anokhin Research Institute of Normal Physiology, Moscow, Russia
Keywords: gastroesophageal reflux disease, Emalan, Parodontax-F, gustometry, taste perception

Abstract

Taste perception is an important criterion for the state of the oral mucous membrane in patients with gastroesophageal reflux disease. The tongue, as an organ of taste, is characterized by serious changes in the functional state after injury with acid-containing substrates due to reflux. The specific features of taste perception and possibility for their correction were studied in 75 patients with this disorder. The type of changes in activity of tongue taste receptors and taste thresholds in patients before and after therapy were estimated by means of advanced gustometry and functional mobility technique. Specific changes in sensory function of the oral cavity were shown to be associated with acid aggression. Our results illustrate the possibility of taste correction in patients with gastroesophageal reflux disease. Taking into account some features of the general disease, it can be concluded that the introduction of Parodontax-F toothpaste and Emalan into combined therapy is accompanied by the improvement of taste perception. Correction of dysgeusia is an important criterion for the improvement of the quality of life of patients.

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Published
2015-07-09
How to Cite
Budylina S. M., Dmitrieva L. A., Kostina N. V., Georgieva O. A., Pertsov S. S. Taste perception during clinical symptom complex of gastroesophageal reflux disease // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2015. VOL. 59. № 2. PP. 51–56.
Section
Original research