Prospects for the Use of Cells Possessing Myogenic Potential in the Treatment of Skeletal Muscle Diseases: a Review of Research. Part 2 –Populations of stem cells of muscle and non-muscle origin

  • V. L. Zorin A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia; Human Stem Cells Institute, Moscow, Russia
  • A. I. Zorina Human Stem Cells Institute, Moscow, Russia
  • A. A. Pulin A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
  • P. B. Kopnin N.N. Blokhin Cancer Research Center of RAMS, Moscow, Russia
  • I. I. Eremin A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
Keywords: muscular dystrophy, cell therapy, stem cells, side population cells, mesoangioblasts, multipotent mesenchymal stromal cells, muscle stem cells with myogenic potential, stem cells of non-muscle origin with myogenic potential

Abstract

The paper reviews research results of myogenic potential, specific properties, functions, and phenotypic features of a number of stem cells populations of muscle and non-muscle origin, their ability to participate in the restoration of the physiological homeostasis of skeletal muscle. The results of scientific research allow to predict with high probability the establishment of an effective cell technology to treat degenerative muscle diseases.

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Published
2015-11-11
How to Cite
Zorin V. L., Zorina A. I., Pulin A. A., Kopnin P. B., Eremin I. I. Prospects for the Use of Cells Possessing Myogenic Potential in the Treatment of Skeletal Muscle Diseases: a Review of Research. Part 2 –Populations of stem cells of muscle and non-muscle origin // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2015. VOL. 59. № 3. PP. 106–117.
Issue
Vol. 59 No. 3 (2015)
Section
Reviews