Autoantibodies to glutamate and GABA in opiate addiction

  • L. A. Vetrile The Institute of General Pathology and Pathophysiology, Moscow, Russia
  • V. G. Fomina The Institute of General Pathology and Pathophysiology, Moscow, Russia
  • T. I. Nevidimova Mental Health Research institute, Tomsk, Russia
  • T. P. Vetlugina Mental Health Research institute, Tomsk, Russia
  • E. I. Batukhtina Mental Health Research institute, Tomsk, Russia
  • D. N. Savochkina Mental Health Research institute, Tomsk, Russia
  • I. A. Zakharova The Institute of General Pathology and Pathophysiology, Moscow, Russia
  • T. V. Davydova The Institute of General Pathology and Pathophysiology, Moscow, Russia
Keywords: autoantibodies, drug addiction, glutamate, GABA

Abstract

Blood serum from 129 patients with opium addiction at different stages of the disease and 63 donors (control group) was examined for the presence of autoantibodies to the exciting and inhibitory amino acids glutamate and GABA. It was shown enhanced production of autoantibodies to glutamate and GABA. Dependence of the level and frequency of detection of autoantibodies to glutamate and GABA on the stage of the disease was revealed.

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Published
2015-11-11
How to Cite
Vetrile L. A., Fomina V. G., Nevidimova T. I., Vetlugina T. P., Batukhtina E. I., Savochkina D. N., Zakharova I. A., Davydova T. V. Autoantibodies to glutamate and GABA in opiate addiction // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2015. VOL. 59. № 3. PP. 38–43.
Issue
Vol. 59 No. 3 (2015)
Section
Original research