Comparison of neuroprotective effects of derivatives of eritropoetine by different way of bringing in drugs with model of bilateral photochemically induced thrombosis of the prefrontal cortex of rat brain
Keywords:
photothrombosis, prefrontal cortex, derivatives of eritropoetine: Epo Epo-Fc Epo-Tr, neuroprotective and antiamnestic action, intranasal and intraperitoneal injection
Abstract
It was stated with model of bilateral photochemically induced thrombosis of the prefrontal cortex by injected intranasally or intraperitoneally in 1h after operation new derivatives of eritropoetine : Epo, Epo-Fc, Epo-Tr provoked neuroprotective and antiamnestic action. Epo-Fc demonstrated more effective action by intranasal injection.Downloads
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Published
2015-11-11
How to Cite
Shakova F. M., Kalinina T. I., Barskov I. V., Stelmashuk E. V., Genrixc E. E., Yrin V. L., Romanova G. A. Comparison of neuroprotective effects of derivatives of eritropoetine by different way of bringing in drugs with model of bilateral photochemically induced thrombosis of the prefrontal cortex of rat brain // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2015. VOL. 59. № 3. PP. 28–33.
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Original research