Role of endothelial dysfunction in the development of vascular complications of diabetes

  • I.N. Turenkov Volgograd State Medical University, 3, Pugachev str., Volgograd, 400001, Russia
  • A.V. Voronkov Volgograd State Medical University, 3, Pugachev str., Volgograd, 400001, Russia
  • A.A. Slietsans Volgograd State Medical University, 3, Pugachev str., Volgograd, 400001, Russia
Keywords: endothelial dysfunction, diabetes, nitric oxide

Abstract

The literature review discusses the main pathological factors (hyperinsulinemia, hyperglycemia, insulin resistance, oxidative stress, neurohormonal activation, disturbances in the synthesis system, allocation and availability of nitric oxide, etc.) that underlie the development of endothelial dysfunction in diabetes mellitus and determine their role in the development and progression of vascular complications of this disease.

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Published
2013-06-19
How to Cite
Turenkov I., Voronkov A., Slietsans A. Role of endothelial dysfunction in the development of vascular complications of diabetes // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2013. VOL. 57. № 2. PP. 80–84.
Issue
Vol. 57 No. 2 (2013)
Section
Reviews