Brain blood flow and cerebral insult. Part 2. Cerebral insult pathogenesis and therapy

Abstract

The data relating to the pathogenesis of cerebral stroke, and the role of nitric oxide in the mechanism of its development is presented. Information on the changes of the expression levels of enzymes NOS, concentrations of nitric oxide and its metabolites in the ischemic regions of the brain is analyzed. The data on the connection between the NOS with other enzyme systems is shown. The possibilities of the use of nitric oxide in cerebral stroke are discussed.