Experimental model of severe local radiation injuries of the skin after X-rays

  • K.V. Kotenko Burnazyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 46, Zhivopisnay str., Moscow, 123182, Russia
  • B.B. Moroz Burnazyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 46, Zhivopisnay str., Moscow, 123182, Russia
  • T.A. Nasonova Burnazyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 46, Zhivopisnay str., Moscow, 123182, Russia
  • O.A. Dobrynina Burnazyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 46, Zhivopisnay str., Moscow, 123182, Russia
  • A.A. Lipengolz Burnazyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 46, Zhivopisnay str., Moscow, 123182, Russia
  • T.I. Gimadova Burnazyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 46, Zhivopisnay str., Moscow, 123182, Russia
  • Yu.B. Deshevoy Burnazyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 46, Zhivopisnay str., Moscow, 123182, Russia
  • V.G. Lebedev Burnazyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 46, Zhivopisnay str., Moscow, 123182, Russia
  • A.V. Lyrschikova Burnazyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 46, Zhivopisnay str., Moscow, 123182, Russia
  • I.I. Eremin Burnazyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 46, Zhivopisnay str., Moscow, 123182, Russia
Keywords: skin, X-ray, local radiation injury, mesenchymal stem cells

Abstract

The experimental model of severe local radiation injuries skin under the influence of a relatively soft X-rays on a modified device RAP 100-10 produced by «Diagnostica-M» (Russia) was proposed. The model can be used as pre-clinical studies in small experimental animals in order to improve the treatment of local radiation injuries, especially in the conditions of application of cellular therapy.

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Published
2013-11-29
How to Cite
Kotenko K., Moroz B., Nasonova T., Dobrynina O., Lipengolz A., Gimadova T., Deshevoy Y., Lebedev V., Lyrschikova A., Eremin I. Experimental model of severe local radiation injuries of the skin after X-rays // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2013. VOL. 57. № 4. PP. 121–123.
Issue
Vol. 57 No. 4 (2013)
Section
Methods