Mass-spectrometry in biology and medicine of XXI Century

  • E.D. Virus Institute of General Pathology and Pathophysiology, RAMS, 8, Baltiyskaya str., 125315, Moscow, Russia
  • A.V. Ivanov Institute of General Pathology and Pathophysiology, RAMS, 8, Baltiyskaya str., 125315, Moscow, Russia
  • B.P. Luzyanin Institute of General Pathology and Pathophysiology, RAMS, 8, Baltiyskaya str., 125315, Moscow, Russia
  • A.A. Paltsyn Institute of General Pathology and Pathophysiology, RAMS, 8, Baltiyskaya str., 125315, Moscow, Russia
  • A.A. Kubatiev Institute of General Pathology and Pathophysiology, RAMS, 8, Baltiyskaya str., 125315, Moscow, Russia
Keywords: mass spectrometry, mass analyzers, ion trap mass spectrometry, quadrupole mass spectrometry, orbitrap, time-of-light mass spectrometry

Abstract

This article for those who faces for the first time with mass spectrometry, but for obvious reasons they don’t want to refer to mass spectrometers as to «black boxes». In this article all mass spectrometers which are used in analytical practice are mentioned. The huge need of analytical practice for very sensitive and selective methods of detection have stimulated the attraction of various mass analyzers by mass spectral laboratories. The concentration of analytes, requirements for limit of detection and sample content define the choice of the device.

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Published
2013-11-29
How to Cite
Virus E., Ivanov A., Luzyanin B., Paltsyn A., Kubatiev A. Mass-spectrometry in biology and medicine of XXI Century // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2013. VOL. 57. № 4. PP. 68–75.
Section
Reviews