Morpho-biophysical research of erythrocytes of intact and vagotomized rats in various terms after the acute hemorrhage

  • A.Yu. Tsibulevsky Russian national research medical university, 117997, Moscow, Ostrovityanov str., 1
  • T.K. Dubovaya Russian national research medical university, 117997, Moscow, Ostrovityanov str., 1
  • A.G. Maksina Russian national research medical university, 117997, Moscow, Ostrovityanov str., 1
  • B.Z. Sokolinsky Medical computer systems (Mekos), 117437, Academician Volgin str., 33
  • A.M. Pyatnitsky Russian national research medical university, 117997, Moscow, Ostrovityanov str., 1
  • V.S. Medovy Medical computer systems (Mekos), 117437, Academician Volgin str., 33
  • V.E. Anisimova Russian national research medical university, 117997, Moscow, Ostrovityanov str., 1
Keywords: hemorrhage, vagotomy, erythrocytes, morphology, membrane microviscosity

Abstract

The acute massive hemorrhage (35—37% of the blood volume) at rats is accompanied by changes of morphological (diameter, the area, polarizations, the form-factor, integrated and specific absorbency) and biophysical (a relief of a surface and microviscosity of a lipid phase of plasmolemma) characteristics of erythrocytes. Thus character and dynamics of response of erythron initially intact and vagotomized (14 days after operation) animals essentially differ: the former demonstrate significant changes in 3—10 h and 240 h and the latter — in 0,5 h and 96 h.

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Published
2013-01-21
How to Cite
Tsibulevsky A., Dubovaya T., Maksina A., Sokolinsky B., Pyatnitsky A., Medovy V., Anisimova V. Morpho-biophysical research of erythrocytes of intact and vagotomized rats in various terms after the acute hemorrhage // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2013. VOL. 57. № 1. PP. 50–55.
Issue
Vol. 57 No. 1 (2013)
Section
Original research