Функциональные грани дофаминергической системы и рак (часть 1)

Evgeny V. Bocharov; Valerian G. Kucheryanu; Olga A. Bocharova

doi:10.25557/0031-2991.2017.03.116-126

Evgeny V. Bocharov N.N.Blokhin Russian Cancer Research Center, Moscow http://orcid.org/0000-0003-2342-9881
Valerian G. Kucheryanu Institute of General Pathology and Pathophysiology, Moscow http://orcid.org/0000-0002-5071-3581
Olga A. Bocharova Institute of General Pathology and Pathophysiology, Moscow http://orcid.org/0000-0002-6365-2888

DOI: https://doi.org/10.25557/0031-2991.2017.03.116-126

Keywords: dopaminergic system; dopamine receptors; aging; stress; depression; Parkinson’s desease.

Abstract

The review is devoted to multifunctional properties of dopaminergic system. Dopamine is synthesized in the central nervous system and gastrointestinal tract. The first part of the review presents the current literature data on the role of dopamine in the aging process. We also discuss the mechanisms underlying depressive disorder in terms of participation of the dopaminergic system to bring together some concepts: monoaminergic, inflammatory, epigenetic, neurotrophins and anti-apoptotic.

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Functional facets of dopaminergic system and cancer. Part 1

Abstract

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