Skin microbiome in adult atopic dermatitis

  • O. V. Kandalova A.I. Evdokimov Moscow State Medical and Dental University, 127473, Moscow, 20 Delegatskaya St.
  • I. V. Elistratova The Central military hospital of the National Guard of Russian Federation, Moscow region; Balashikha, Nikolo-Arkhangelskoe, 101 Vishnyakovskoye Sh.; The Institute of General Pathology and Pathophysiology, Moscow
  • O. B. Ivanchenko Peter the Great St. Petersburg Polytechnic University, Graduate school of Biotechnology and Food Science, 194021, St-Petersburg, 50 Novorossiyskaya St.
  • A. V. Grechko Federal scientific and clinical center of resuscitation and rehabilitation, Moscow region, Solnechnogorsk district, village Lytkino, d. 777
  • S. G. Morozov The Institute of General Pathology and Pathophysiology, Moscow
DOI: https://doi.org/10.25557/0031-2991.2018.04.209-214
Keywords: atopic dermatitis, skin microbiome, S. aureaus

Abstract

In this mini review we have analyzed the role of skin microbiome in the atopic dermatitis relapse in adults, in particular, a role of S. aureaus in this process. The background for the skin bacterial contamination under the influence of environmental factors has been analyzed. We reviewed some S. aureaus effects on the components of innate and adaptive immunity due to the secretion of specific regulatory proteins, a number of proteolytic enzymes, and some hydrolases. There were indicated some ways to eliminate the bacterial infection to prevent the atopic dermatitis relapse in adults

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Published
2018-11-21
How to Cite
Kandalova O. V., Elistratova I. V., Ivanchenko O. B., Grechko A. V., Morozov S. G. Skin microbiome in adult atopic dermatitis // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2018. VOL. 62. № 4. PP. 209–214.
Issue
Vol. 62 No. 4 (2018)
Section
Reviews