Surfactant system of lung in rats with different resistance to stress under alloxan diabetes

  • N. N. Vasiljeva Izhevsk State Medical Academy, 281, Kommunarov str., Izhevsk, 426034
  • I. G. Bryndina Izhevsk State Medical Academy, 281, Kommunarov str., Izhevsk, 426034
  • S. V. Protasova Izhevsk State Medical Academy, 281, Kommunarov str., Izhevsk, 426034
  • E. G. Butolin Izhevsk State Medical Academy, 281, Kommunarov str., Izhevsk, 426034
Keywords: pulmonary surfactant, alloxan diabetes, individual stress resistance

Abstract

It is shown that the surface active properties of lung under experimental diabetes mellitus was decreased on the background of increased LPL content in alveolar space. Surfactant changes correlated with the level of glucose, glycosylated hemoglobin and 11-oxycorticosteroids in blood. The obtained results indicate that the degree of impairment in the pulmonary surfactant system in alloxan diabetes depends on the resistance or susceptibility of animals to stress.

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Published
2014-02-02
How to Cite
Vasiljeva N. N., Bryndina I. G., Protasova S. V., Butolin E. G. Surfactant system of lung in rats with different resistance to stress under alloxan diabetes // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2014. VOL. 58. № 1. PP. 44–47.
Issue
Vol. 58 No. 1 (2014)
Section
Original research