The functional status of pregnant women hemostasis according to the «global» low-frequency piezothromboelastography test

  • I. I. Tyutrin Siberian State Medical University, 2, Moscowski Trakt, Tomsk, 634050, Russia
  • V. V. Udut Federal State Institution Research Institute of Pharmacology named E.D. Goldberg, Siberian Branch of the Russian Academy of Medical Sciences, 3, Lenina avenue, Tomsk, 634028, Russia
  • V. F. Klimenkova Regional Perinatal Center, 96/1, Ivana Chernikch street, Tomsk, 634036, Russia
Keywords: hemostatic potential, low-frequency piezothrombelastography, syndrome of the general circulator adaptation

Abstract

This paper presents the research of the hemostatic whole blood’s potential of healthy and pregnant women (39—40 weeks) according to the clinical data using the «global» low-frequency piezothromboelastography. Three types of the hemostatic potential (hypo-, normal- and hipercoagulative) are exposed in the status of the physiological optimum. It is shown that when forming the syndrome of the general circulator adaptation of the organism to the pregnancy and the childbirth is accompanied by intensification of thrombin activity and compensatory strengthening of total antihaemostatic activity. It is shown that only the timely research of the whole blood with aliquoties of endotelium (a number of them effects in the bounded time duration) producers tests, blood corpuscle and hemostasis factors, can provide the unbiased information about «time sample» of the hemostatic potential status.

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Published
2014-06-12
How to Cite
Tyutrin I. I., Udut V. V., Klimenkova V. F. The functional status of pregnant women hemostasis according to the «global» low-frequency piezothromboelastography test // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2014. VOL. 58. № 2. PP. 61–67.
Section
Original research