The cognitive disorders and raised free-radical activity of a brain of posterity of rats-females with experimental chronic alcoholic pathology of a liver

  • V. A. Vakhnin South-Ural State medical university, 454092, Chelyabinsk, Russian Federation
  • Gennady V. Brukhin South-Ural State medical university, 454092, Chelyabinsk, Russian Federation
Keywords: liver disease, alcohol, degradation of lipids, Morris water maze

Abstract

It is established, that chronic alcoholic defeat of hepatobiliarity sistems leads to infringement of cognitive functions at posterity. At the given group of animals revealed distress of memory and ability to orientation in space in the conditions of Morris water maze is, the research behavior is oppressed. Besides, the animals, born from mothers with chronic alcoholic defeat of hepatobiliarity systems have raised free-radical activity, which plays an important role in maintenance of adaptive possibilities of a brain.

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Published
2014-09-12
How to Cite
Vakhnin V. A., Brukhin G. V. The cognitive disorders and raised free-radical activity of a brain of posterity of rats-females with experimental chronic alcoholic pathology of a liver // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2014. VOL. 58. № 3. PP. 58–62.
Issue
Vol. 58 No. 3 (2014)
Section
Original research