Index assessment of parameters of the cardiovascular system functioning in post-stroke patients

Abstract

Introduction. Objective characteristics of the cardiovascular system (CVS) functioning are important indicators of the physiological state and adaptive reserves of the human body. Aim. Index assessment of the state of peripheral circula tion and parameters of the balance between the CVS cardiac and vascular components during the 2nd stage of rehabil itation in patients after ischemic stroke depending on their gender and age.Methods. The CVS functional state was studied in 66 patients aged 41 to 83 years at the 2nd stage of rehabilitation after ischemic stroke. The patients underwent a rehabilitation program daily for 2 weeks, including exercise therapy using additional mechanical therapeutic devices, therapeutic massage, equipment-based physiotherapy, and drug therapy. On days 1 and 10 of the rehabilitation treatment, daily Holter monitoring of electrocardiogram and blood pressure was per formed. Heart rate (HR) and blood pressure (BP) parameters were recorded. To assess the dynamics of the CVS func tional state and adaptive potential, CVS function indices were calculated.Results. An integrated assessment of the CVS functional state allows analyzing the mobilization of the body’s adap tive capabilities during rehabilitation treatment. The values of the physiological normal range of hemodynamic indices were calculated as the proper total and specific peripheral vascular resistance (PTPVR and PSPVR), proper minute blood volume and cardiac index (PMBV and PCI), indices of cardiac function and vascular tone (HWI and VTI), and the integral indicator of the balance of the cardiac and vascular components (IIBCVC). Statistically significant (p<0.05) decreases in TPVR and KTPVR and an increase in PTPVR were observed. In the total group (n=66), a positive trend in the CVS func tioning was noted in 83.33% of cases.Conclusion. The use of indices for integrated assessment of the CVS functional state during post-ischemic stroke reha bilitation is relevant and pathogenetically justified. In general, there was a tendency for positive dynamics of CVS func tioning and its adaptive potential that confirmed the effectiveness of the rehabilitation activities. The above asses sment methods can be proposed for monitoring the effectiveness of rehabilitation in post-stroke patients and for scheduling rehabilitation measured at stage 3.