Study of intima-medial thickness (IMT) of the carotid arteries as an indicator of natural atherosclerosis progress in Moscow population

  • V.A. Myasoedova Institute for Atherosclerosis Research, Russian Academy of Natural Sciences, Institute for Atherosclerosis Research, Skolkovo Innovative Center, 143025, 100 Novaya Str., Moscow, Russia; The Institute for General Pathology and Pathophysiology RAMS, 8, Baltiyskaya str., Moscow, 125315, Russia
  • T.V. Kirichenko Institute for Atherosclerosis Research, Russian Academy of Natural Sciences, Institute for Atherosclerosis Research, Skolkovo Innovative Center, 143025, 100 Novaya Str., Moscow, Russia
  • V.А. Оrekhova Institute for Atherosclerosis Research, Russian Academy of Natural Sciences, Institute for Atherosclerosis Research, Skolkovo Innovative Center, 143025, 100 Novaya Str., Moscow, Russia
  • I.A. Sobenin The Institute for General Pathology and Pathophysiology RAMS, 8, Baltiyskaya str., Moscow, 125315, Russia
  • N.M. Muhamedova Institute for Atherosclerosis Research, Russian Academy of Natural Sciences, Institute for Atherosclerosis Research, Skolkovo Innovative Center, 143025, 100 Novaya Str., Moscow, Russia
  • D.M. Martirosyan Institute for Atherosclerosis Research, Russian Academy of Natural Sciences, Institute for Atherosclerosis Research, Skolkovo Innovative Center, 143025, 100 Novaya Str., Moscow, Russia
  • V.P. Karagodin Plekhanov Russian University of Economics, 36, Stremyannyi per., Moscow, 117997, Russia
  • А.N. Оrekhov Institute for Atherosclerosis Research, Russian Academy of Natural Sciences, Institute for Atherosclerosis Research, Skolkovo Innovative Center, 143025, 100 Novaya Str., Moscow, Russia; The Institute for General Pathology and Pathophysiology RAMS, 8, Baltiyskaya str., Moscow, 125315, Russia
Keywords: carotid arteries, intima-medial thickness, ultrasonic scanning, atherosclerosis, gender differences

Abstract

A cross-sectional study of intima-medial thickness (IMT) of the carotid arteries in men and women in different age groups was performed as well as a prospective study of the dynamics of carotid IMT changes. It was shown that at the ages 40—70 years IMT is higher in men then in women, but at age after 70 such difference disappears due to acceleration of atherosclerosis progression in women, which starts after 58. Atherosclerosis progresses at uneven rate, both in men and women, and there are age periods characterized with different rate of IMT progression. In women, the most active progression of atherosclerosis starts 8 years later than in men, and is associated with the onset of late menopausal period.

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Published
2012-12-20
How to Cite
Myasoedova V., Kirichenko T., Оrekhova V., Sobenin I., Muhamedova N., Martirosyan D., Karagodin V., Оrekhov А. Study of intima-medial thickness (IMT) of the carotid arteries as an indicator of natural atherosclerosis progress in Moscow population // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2012. VOL. 56. № 3. PP. 104–108.
Section
Original research