Systemic errors in the estimation of systemic arterial pressure via transfer functions after experimental changes of the circulating blood volume

  • V. O. Erkudov Saint-Petersburg State Pediatric Medical University, Saint-Petersburg; I.P. Pavlov Institute of Physiology of the Russian Academy of Science, Saint-Petersburg
  • A. P. Pugovkin Saint-Petersburg State Pediatric Medical University, Saint-Petersburg
  • N. A. Verlov B.P. Konstantinov Petersburg Nuclear Physics Institute, Gatchina, Russia
  • I. V. Sergeev I.P. Pavlov Institute of Physiology of the Russian Academy of Science, Saint-Petersburg
  • S. A. Ievkov City Pediatric Hospital № 1, 198205, Saint-Petersburg
Keywords: rat, experiment, systemic arterial pressure, compensation of circulating blood volume, haemorrhage, transfer functions

Abstract

The results of the experimental studies reveal the decrease of vascular rigidity with the increase of systemic error of the arterial pressure values estimated via implication of transfer functions following haemorrhage modeling in rats. Compensation of the circulating blood volume by means of dextran infusion resulted in restoration of both vascular rigidity and systemic error of estimated arterial pressure. The results can be put into medical practice as an approach for testing of non-invasive methods in cardiovascular research.

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Published
2016-03-22
How to Cite
Erkudov V. O., Pugovkin A. P., Verlov N. A., Sergeev I. V., Ievkov S. A. Systemic errors in the estimation of systemic arterial pressure via transfer functions after experimental changes of the circulating blood volume // Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 2016. VOL. 60. № 1. PP. 45–49.
Issue
Vol. 60 No. 1 (2016)
Section
Original research