Нейрогенез в зрелом мозге человека. Обоснование терапевтического подхода

  • Олег Александрович Гомазков
Ключевые слова: нейрогенез зрелого мозга; гиппокамп; новые нейроны в мозге человека; мишени репаративной терапии.

Аннотация

Нейроны взрослого мозга, формирующиеся в процессе нейрогенеза, являются непременными участниками важных физиологических процессов. Новые клетки играют важную роль в поддержке когнитивных функций, обучения и памяти. Эндогенная активация нейральных прогениторных клеток отмечена в ответ на патологические изменения — ишемия, нейродегенеративные заболевания, физическая травма, психические расстройства. Однако на фоне большого числа исследований, выполняемых в эксперименте, понимание роли новых клеток в мозге человека остается предметом больших сомнений. Задача данной статьи — проанализировав информацию о нейрогенезе в мозге ЧЕЛОВЕКА, обозначить звенья эндогенной регуляции и обрисовать возможные «мишени» репаративной терапии.

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Опубликован
2017-12-18
Как цитировать
Гомазков О. А. Нейрогенез в зрелом мозге человека. Обоснование терапевтического подхода // Патологическая физиология и экспериментальная терапия. 2017. Т. 61. № 4. С. 126-135.
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